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CMap Candidate Details

Structure:
CMap ID: C05643
Pert ID: BRD-K73610817
Compound Name: UC-112
Targets: XIAP
MoA: XIAP inhibitor
SMILES: Oc1c(CN2CCCC2)cc(COCc2ccccc2)c2cccnc12
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
14019 BRD-K73610817 A375 10 uM 6 h -0.27 -1.13 0.41 0.0 0.0 0.0
14323 BRD-K73610817 A549 10 uM 6 h -0.28 -1.15 0.43 -0.27 -0.92 0.33
14514 BRD-K73610817 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
14883 BRD-K73610817 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
15235 BRD-K73610817 HT29 10 uM 6 h -0.29 -1.2 0.56 0.0 0.0 0.0
15390 BRD-K73610817 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
15660 BRD-K73610817 PC3 10 uM 24 h -0.26 -1.06 0.26 0.0 0.0 0.0
15975 BRD-K73610817 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).