CMap Candidate Details
Structure:
| CMap ID: | C05659 |
| Pert ID: | BRD-K74236984 |
| Compound Name: | UNC0321 |
| Targets: | EHMT2 |
| MoA: | histone lysine methyltransferase inhibitor |
| SMILES: | COc1cc2c(NC3CCN(C)CC3)nc(nc2cc1OCCOCCN(C)C)N1CCCN(C)CC1 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 8978 | BRD-K74236984 | A375 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 9116 | BRD-K74236984 | A549 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 9881 | BRD-K74236984 | HA1E | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.28 | -0.95 | 0.4 |
| 10124 | BRD-K74236984 | HCC515 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 10586 | BRD-K74236984 | HCT116 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 10843 | BRD-K74236984 | HEPG2 | 10 uM | 6 h | 0.2 | 0.84 | 0.0 | 0.0 | 0.0 | 0.0 |
| 11011 | BRD-K74236984 | HT29 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 11139 | BRD-K74236984 | MCF??7.00 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.38 | 1.33 | 1.72 |
| 11567 | BRD-K74236984 | NCIH2073 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 12124 | BRD-K74236984 | NCIH596 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 12940 | BRD-K74236984 | THP1 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 13351 | BRD-K74236984 | U937 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 13674 | BRD-K74236984 | VCAP | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 95748 | BRD-K74236984 | NPC | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | -0.25 | -0.83 | 0.16 |
| 95933 | BRD-K74236984 | YAPC | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | -0.37 | -1.23 | 1.28 |
| 96806 | BRD-K74236984 | PC3 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.27 | -0.92 | 0.33 |