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CMap Candidate Details

Structure:
CMap ID: C05677
Pert ID: BRD-K88052444
Compound Name: urea
Targets: ARG1|CA2|CTNNB1
MoA: hydroxy radical formation stimulant
SMILES: NC(N)=O
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
52937 BRD-K88052444 HEPG2 40 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121743 BRD-K88052444 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121775 BRD-K88052444 HELA 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121807 BRD-K88052444 HT29 1.11 uM 24 h 0.0 0.0 0.0 -0.19 -0.62 0.0
121824 BRD-K88052444 MCF??7.00 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121852 BRD-K88052444 PC3 0.37 uM 24 h 0.0 0.0 0.0 -0.33 -1.11 0.9
121874 BRD-K88052444 YAPC 10 uM 24 h 0.0 0.0 0.0 -0.45 -1.51 15.35
129770 BRD-K88052444 A375 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129849 BRD-K88052444 HEK293 0.03 uM 24 h 0.0 0.0 0.0 0.33 1.16 0.91
129974 BRD-K88052444 MCF10A 0.03 uM 24 h -0.22 -0.92 0.06 0.0 0.0 0.0
130060 BRD-K88052444 MDAMB231 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130131 BRD-K88052444 THP1 0.03 uM 24 h 0.21 0.86 0.01 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).