CMap Candidate Details
Structure:
| CMap ID: | C05712 |
| Pert ID: | BRD-K70163715 |
| Compound Name: | vatalanib |
| Targets: | EGFR|FLT1|FLT4|KDR|PDGFRB |
| MoA: | KIT inhibitor; PDGFR tyrosine kinase receptor inhibitor; VEGFR inhibitor |
| SMILES: | Clc1ccc(Nc2nnc(Cc3ccncc3)c3ccccc23)cc1 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 51747 | BRD-K70163715 | MCF??7.00 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | -0.34 | -1.13 | 0.99 |
| 51840 | BRD-K70163715 | PC3 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.21 | -0.71 | 0.03 |
| 90962 | BRD-K70163715 | HUH7 | 10 uM | 72 h | -0.26 | -1.08 | 0.28 | 0.0 | 0.0 | 0.0 |