CMap Candidate Details
Structure:
| CMap ID: | C05745 |
| Pert ID: | BRD-K89704198 |
| Compound Name: | vincamine |
| Targets: | CHRM1|CHRM2|CHRM3|CHRM4 |
| MoA: | adrenergic receptor antagonist |
| SMILES: | CC[C@@]12CCCN3CCc4c([C@H]13)n(c1ccccc41)[C@@](O)(C2)C(=O)OC |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 121812 | BRD-K89704198 | HT29 | 0.125 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.36 | -1.21 | 1.24 |
| 121856 | BRD-K89704198 | PC3 | 1.11 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.23 | -0.77 | 0.08 |
| 129773 | BRD-K89704198 | A375 | 0.03 uM | 24 h | 0.23 | 0.97 | 0.08 | 0.0 | 0.0 | 0.0 |
| 129805 | BRD-K89704198 | HA1E | 0.03 uM | 24 h | -0.34 | -1.42 | 1.43 | 0.0 | 0.0 | 0.0 |
| 129857 | BRD-K89704198 | HEK293 | 0.08 uM | 24 h | -0.17 | -0.72 | 0.0 | 0.0 | 0.0 | 0.0 |
| 129885 | BRD-K89704198 | HELA | 0.01 uM | 24 h | 0.23 | 0.96 | 0.08 | -0.3 | -1.02 | 0.6 |
| 129982 | BRD-K89704198 | MCF10A | 0.08 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 130015 | BRD-K89704198 | MCF??7.00 | 0.03 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 130068 | BRD-K89704198 | MDAMB231 | 2.22 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 130139 | BRD-K89704198 | THP1 | 0.01 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.33 | -1.11 | 0.9 |
| 130175 | BRD-K89704198 | YAPC | 0.01 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |