CMap Candidate Details
Structure:
| CMap ID: | C05747 |
| Pert ID: | BRD-K59753975 |
| Compound Name: | vindesine |
| Targets: | TUBB|TUBB1 |
| MoA: | tubulin polymerization inhibitor |
| SMILES: | CC[C@]1(O)C[C@H]2CN(C1)CCc1c([nH]c3ccccc13)[C@@](C2)(C(=O)OC)c1cc2c(cc1OC)N(C)[C@@H]1[C@]22CCN3CC=C[C@](CC)([C@@H]23)[C@@H](O)[C@]1(O)C(N)=O |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 24461 | BRD-K59753975 | A375 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 24690 | BRD-K59753975 | A549 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | -0.38 | -1.29 | 1.53 |
| 24929 | BRD-K59753975 | HT29 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 25100 | BRD-K59753975 | MCF??7.00 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 25174 | BRD-K59753975 | PC3 | 10 uM | 24 h | -0.31 | -1.27 | 0.74 | -0.32 | -1.07 | 0.77 |
| 25398 | BRD-K59753975 | VCAP | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 91277 | BRD-K59753975 | HUH7 | 4 uM | 72 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |