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CMap Candidate Details

Structure:
CMap ID: C05800
Pert ID: BRD-K36198571
Compound Name: WAY-170523
Targets: MMP13
MoA: metalloproteinase inhibitor
SMILES: Cc1cc(C)c(N(Cc2ccccc2)S(=O)(=O)c2ccc(OCCNC(=O)c3cc4ccccc4o3)cc2)c(c1)C(=O)NO
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4103 BRD-K36198571 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
4424 BRD-K36198571 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
37147 BRD-K36198571 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
37379 BRD-K36198571 A549 10 uM 6 h -0.23 -0.98 0.12 -0.23 -0.77 0.09
37643 BRD-K36198571 ASC 10 uM 24 h 0.22 0.91 0.03 0.0 0.0 0.0
37897 BRD-K36198571 HEPG2 10 uM 6 h -0.22 -0.93 0.07 0.0 0.0 0.0
38075 BRD-K36198571 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
38268 BRD-K36198571 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
38469 BRD-K36198571 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
38945 BRD-K36198571 SKB 10 uM 24 h 0.0 0.0 0.0 -0.29 -0.97 0.44
90361 BRD-K36198571 PC3 0.12 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
90402 BRD-K36198571 VCAP 3.33 uM 24 h 0.0 0.0 0.0 -0.34 -1.16 1.09
99886 BRD-K36198571 U2OS 10 uM 6 h 0.0 0.0 0.0 0.3 1.05 0.57
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).