CMap Candidate Details
Structure:
| CMap ID: | C05819 |
| Pert ID: | BRD-K87343924 |
| Compound Name: | wortmannin |
| Targets: | PI4KA|PI4KB|PIK3CA|PIK3CD|PIK3CG|PIK3R1|PLK1|PRKDC |
| MoA: | PI3K inhibitor |
| SMILES: | COC[C@H]1OC(=O)c2coc3c2[C@@]1(C)C1=C([C@@H]2CCC(=O)[C@@]2(C)C[C@H]1OC(C)=O)C3=O |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 5806 | BRD-K87343924 | HCC515 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.34 | 1.19 | 1.03 |
| 6598 | BRD-K87343924 | VCAP | 10 uM | 6 h | 0.23 | 0.98 | 0.09 | 0.0 | 0.0 | 0.0 |
| 115982 | BRD-K87343924 | A375 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 116023 | BRD-K87343924 | A549 | 0.04 uM | 24 h | -0.22 | -0.93 | 0.07 | 0.0 | 0.0 | 0.0 |
| 116062 | BRD-K87343924 | HA1E | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 116152 | BRD-K87343924 | HEPG2 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 116196 | BRD-K87343924 | HT29 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 116232 | BRD-K87343924 | MCF??7.00 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 116272 | BRD-K87343924 | PC3 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.43 | -1.44 | 15.35 |