CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C05839
Pert ID:	BRD-K45875383
Compound Name:	XBD173
Targets:	TSPO
MoA:	benzodiazepine receptor ligand
SMILES:	CCN(Cc1ccccc1)C(=O)Cn1c2nc(ncc2n(C)c1=O)-c1ccccc1
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
125586	BRD-K45875383	A375	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
125615	BRD-K45875383	A549	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
125697	BRD-K45875383	HT29	0.37 uM	24 h	-0.18	-0.74	0.0	0.0	0.0	0.0
125738	BRD-K45875383	HUVEC	0.125 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
125779	BRD-K45875383	JURKAT	0.37 uM	24 h	0.0	0.0	0.0	-0.28	-0.95	0.41
125829	BRD-K45875383	MCF??7.00	10 uM	24 h	0.0	0.0	0.0	-0.21	-0.72	0.04
125895	BRD-K45875383	THP1	3.33 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
125936	BRD-K45875383	YAPC	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
133702	BRD-K45875383	HA1E	2.22 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
133733	BRD-K45875383	HEK293	0.25 uM	24 h	0.0	0.0	0.0	-0.29	-0.99	0.5
133770	BRD-K45875383	HELA	2.22 uM	24 h	0.0	0.0	0.0	-0.31	-1.06	0.73
133860	BRD-K45875383	MCF10A	0.03 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
133915	BRD-K45875383	MDAMB231	2.22 uM	24 h	-0.22	-0.91	0.05	0.0	0.0	0.0
133945	BRD-K45875383	PC3	2.22 uM	24 h	0.21	0.87	0.01	-0.22	-0.74	0.05

Summary