CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C00585
Pert ID:	BRD-A16694057
Compound Name:	BADGE
Targets:	PPARG
MoA:	PPAR receptor antagonist
SMILES:	CC(C)(c1ccc(OCC2CO2)cc1)c1ccc(OCC2CO2)cc1
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
5389	BRD-A16694057	HA1E	10 uM	6 h	-0.23	-0.97	0.11	0.0	0.0	0.0
5501	BRD-A16694057	HCC515	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
5972	BRD-A16694057	HT29	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
6124	BRD-A16694057	PC3	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
6311	BRD-A16694057	VCAP	10 uM	24 h	0.24	1.02	0.12	0.0	0.0	0.0
41649	BRD-A16694057	A375	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
41998	BRD-A16694057	A549	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
42180	BRD-A16694057	ASC	10 uM	24 h	0.0	0.0	0.0	-0.29	-0.97	0.45
42525	BRD-A16694057	HEPG2	10 uM	6 h	-0.22	-0.9	0.04	-0.31	-1.03	0.64
43252	BRD-A16694057	MCF??7.00	10 uM	6 h	0.0	0.0	0.0	-0.24	-0.81	0.13
43697	BRD-A16694057	PHH	10 uM	24 h	0.0	0.0	0.0	-0.34	-1.14	1.02
43994	BRD-A16694057	SKB	10 uM	24 h	0.24	1.02	0.13	0.0	0.0	0.0
98970	BRD-A16694057	NEU	10 uM	6 h	-0.25	-1.05	0.24	0.29	1.01	0.45
99195	BRD-A16694057	NPC	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0

Summary