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CMap Candidate Details

Structure:
CMap ID: C05869
Pert ID: BRD-K48488978
Compound Name: YM-201636
Targets:
MoA: PI3K inhibitor
SMILES: Nc1ccc(cn1)C(=O)Nc1cccc(c1)-c1nc(N2CCOCC2)c2oc3ncccc3c2n1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
92005 BRD-K48488978 A375 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
92030 BRD-K48488978 BT20 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
92080 BRD-K48488978 HA1E 10 uM 24 h 0.24 1.01 0.12 0.28 0.99 0.39
92114 BRD-K48488978 HCC515 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
92148 BRD-K48488978 HS578T 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
92199 BRD-K48488978 HT29 1.11 uM 24 h 0.0 0.0 0.0 0.35 1.23 1.24
92222 BRD-K48488978 MCF10A 3.33 uM 24 h 0.27 1.11 0.25 0.0 0.0 0.0
92278 BRD-K48488978 MCF??7.00 10 uM 3 h 0.0 0.0 0.0 0.0 0.0 0.0
92297 BRD-K48488978 MDAMB231 3.33 uM 24 h 0.0 0.0 0.0 0.33 1.16 0.9
92352 BRD-K48488978 PC3 10 uM 24 h 0.21 0.87 0.01 0.0 0.0 0.0
92377 BRD-K48488978 SKBR3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).