CMap Candidate Details
Structure:
| CMap ID: | C05897 |
| Pert ID: | BRD-K92446736 |
| Compound Name: | zatebradine |
| Targets: | HCN1|HCN2|HCN3|HCN4 |
| MoA: | HCN channel blocker |
| SMILES: | COc1ccc(CCN(C)CCCN2CCc3cc(OC)c(OC)cc3CC2=O)cc1OC |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 3069 | BRD-K92446736 | HA1E | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | -0.44 | -1.47 | 15.35 |
| 3288 | BRD-K92446736 | HCC515 | 10 uM | 24 h | -0.19 | -0.79 | 0.0 | 0.0 | 0.0 | 0.0 |
| 3564 | BRD-K92446736 | PC3 | 10 uM | 24 h | 0.37 | 1.52 | 1.45 | -0.36 | -1.2 | 1.18 |
| 3894 | BRD-K92446736 | VCAP | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 39226 | BRD-K92446736 | A375 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 39372 | BRD-K92446736 | A549 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 39828 | BRD-K92446736 | ASC | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 40118 | BRD-K92446736 | HEPG2 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 40535 | BRD-K92446736 | MCF??7.00 | 10 uM | 24 h | 0.19 | 0.79 | 0.0 | 0.0 | 0.0 | 0.0 |
| 41251 | BRD-K92446736 | NPC | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 41590 | BRD-K92446736 | SKB | 10 uM | 24 h | 0.2 | 0.84 | 0.0 | 0.31 | 1.1 | 0.68 |