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CMap Candidate Details

Structure:
CMap ID: C05899
Pert ID: BRD-K64157027
Compound Name: ZD-2079
Targets: ADRB3
MoA: adrenergic receptor agonist
SMILES: O[C@@H](CNCCOc1ccc(CC(O)=O)cc1)c1ccccc1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1766 BRD-K64157027 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
2112 BRD-K64157027 HCC515 10 uM 6 h 0.0 0.0 0.0 -0.28 -0.95 0.4
2407 BRD-K64157027 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
2720 BRD-K64157027 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
41818 BRD-K64157027 A375 10 uM 6 h 0.0 0.0 0.0 0.26 0.91 0.23
41966 BRD-K64157027 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42430 BRD-K64157027 ASC 10 uM 24 h -0.19 -0.79 0.0 0.0 0.0 0.0
42746 BRD-K64157027 HEPG2 10 uM 6 h 0.0 0.0 0.0 -0.33 -1.11 0.92
43045 BRD-K64157027 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43343 BRD-K64157027 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43610 BRD-K64157027 NPC 10 uM 24 h -0.26 -1.08 0.31 -0.24 -0.82 0.14
43912 BRD-K64157027 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
44168 BRD-K64157027 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).