Logo 1 Logo 2

CMap Candidate Details

Structure:
CMap ID: C05901
Pert ID: BRD-K11373525
Compound Name: ZD-7155
Targets: AGTR1
MoA: angiotensin receptor antagonist
SMILES: CCc1cc2N(Cc3ccc(cc3)-c3ccccc3-c3nnn[nH]3)C(=O)CCc2c(CC)n1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1544 BRD-K11373525 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
1886 BRD-K11373525 HCC515 10 uM 24 h 0.0 0.0 0.0 0.24 0.83 0.12
2743 BRD-K11373525 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
41909 BRD-K11373525 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42294 BRD-K11373525 ASC 10 uM 24 h 0.26 1.1 0.24 -0.32 -1.08 0.8
42627 BRD-K11373525 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42930 BRD-K11373525 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43292 BRD-K11373525 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43487 BRD-K11373525 NPC 10 uM 24 h 0.0 0.0 0.0 0.19 0.69 0.01
43791 BRD-K11373525 PHH 10 uM 24 h 0.0 0.0 0.0 -0.19 -0.64 0.01
44068 BRD-K11373525 SKB 10 uM 24 h -0.2 -0.85 0.01 0.0 0.0 0.0
97160 BRD-K11373525 A375 3.33 uM 24 h 0.0 0.0 0.0 -0.31 -1.05 0.72
97226 BRD-K11373525 PC3 3.33 uM 24 h -0.29 -1.22 0.61 0.26 0.93 0.27
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).