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CMap Candidate Details

Structure:
CMap ID: C05914
Pert ID: BRD-K67525671
Compound Name: ZK-200775
Targets:
MoA: kainate receptor antagonist
SMILES: OP(O)(=O)Cn1c2cc(N3CCOCC3)c(cc2[nH]c(=O)c1=O)C(F)(F)F
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
124642 BRD-K67525671 HEK293 10 uM 24 h 0.0 0.0 0.0 -0.34 -1.13 0.98
124668 BRD-K67525671 HELA 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124701 BRD-K67525671 HT29 0.04 uM 24 h 0.2 0.84 0.0 0.0 0.0 0.0
124748 BRD-K67525671 MCF10A 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124850 BRD-K67525671 PC3 1.11 uM 24 h -0.19 -0.78 0.0 0.0 0.0 0.0
124892 BRD-K67525671 THP1 0.125 uM 24 h 0.0 0.0 0.0 -0.35 -1.18 1.15
132670 BRD-K67525671 A375 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132699 BRD-K67525671 A549 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132728 BRD-K67525671 HA1E 0.74 uM 24 h 0.27 1.11 0.25 0.0 0.0 0.0
132841 BRD-K67525671 JURKAT 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132907 BRD-K67525671 MCF??7.00 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132920 BRD-K67525671 MDAMB231 0.74 uM 24 h 0.0 0.0 0.0 0.34 1.19 1.03
132963 BRD-K67525671 YAPC 2.22 uM 24 h 0.0 0.0 0.0 -0.23 -0.78 0.09
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).