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CMap Candidate Details

Structure:
CMap ID: C05917
Pert ID: BRD-K91825936
Compound Name: ZK811752
Targets: CCR1
MoA: CC chemokine receptor antagonist
SMILES: C[C@@H]1CN(Cc2ccc(F)cc2)CCN1C(=O)COc1ccc(Cl)cc1NC(N)=O
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
127749 BRD-K91825936 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127793 BRD-K91825936 A549 10 uM 24 h -0.21 -0.88 0.03 0.0 0.0 0.0
127827 BRD-K91825936 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127874 BRD-K91825936 HEK293 10 uM 24 h 0.0 0.0 0.0 -0.3 -1.02 0.61
127903 BRD-K91825936 HT29 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127948 BRD-K91825936 HUVEC 0.125 uM 24 h 0.0 0.0 0.0 -0.19 -0.63 0.01
128001 BRD-K91825936 MCF10A 10 uM 24 h -0.28 -1.17 0.5 0.0 0.0 0.0
128031 BRD-K91825936 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 -0.26 -0.87 0.23
128082 BRD-K91825936 YAPC 1.11 uM 24 h 0.0 0.0 0.0 -0.37 -1.25 1.35
135575 BRD-K91825936 HELA 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135666 BRD-K91825936 JURKAT 2.22 uM 24 h 0.0 0.0 0.0 -0.3 -1.0 0.55
135724 BRD-K91825936 PC3 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).