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CMap Candidate Details

Structure:
CMap ID: C05921
Pert ID: BRD-K19605405
Compound Name: ZM-241385
Targets: ADORA1|ADORA2A|ADORA2B|ADORA3
MoA: adenosine receptor antagonist
SMILES: Nc1nc(NCCc2ccc(O)cc2)nc2nc(nn12)-c1ccco1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
2993 BRD-K19605405 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
3342 BRD-K19605405 HCC515 10 uM 6 h 0.2 0.85 0.0 0.0 0.0 0.0
3603 BRD-K19605405 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
3743 BRD-K19605405 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
44336 BRD-K19605405 A375 10 uM 6 h -0.26 -1.09 0.32 0.0 0.0 0.0
44544 BRD-K19605405 A549 10 uM 24 h -0.25 -1.04 0.22 -0.35 -1.17 1.13
44893 BRD-K19605405 ASC 10 uM 24 h -0.23 -0.96 0.1 0.0 0.0 0.0
45195 BRD-K19605405 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45463 BRD-K19605405 HT29 10 uM 6 h 0.0 0.0 0.0 0.27 0.95 0.31
45670 BRD-K19605405 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 -0.34 -1.14 1.03
46011 BRD-K19605405 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46329 BRD-K19605405 PHH 10 uM 24 h 0.22 0.91 0.04 0.0 0.0 0.0
46645 BRD-K19605405 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
99733 BRD-K19605405 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).