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CMap Candidate Details

Structure:
CMap ID: C05924
Pert ID: BRD-K73789395
Compound Name: ZM-336372
Targets: BRAF|LCK|MAPK14|RAF1
MoA: RAF inhibitor
SMILES: CN(C)c1cccc(c1)C(=O)Nc1ccc(C)c(NC(=O)c2ccc(O)cc2)c1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
9038 BRD-K73789395 A375 100 uM 6 h 0.0 0.0 0.0 -0.25 -0.84 0.18
9228 BRD-K73789395 A549 100 uM 6 h -0.32 -1.33 0.89 0.0 0.0 0.0
9498 BRD-K73789395 AGS 100 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
9802 BRD-K73789395 H1299 100 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10077 BRD-K73789395 HA1E 100 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10173 BRD-K73789395 HCC515 100 uM 24 h -0.29 -1.23 0.63 -0.35 -1.17 1.11
10584 BRD-K73789395 HCT116 100 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10841 BRD-K73789395 HEPG2 100 uM 6 h -0.22 -0.91 0.05 0.0 0.0 0.0
11084 BRD-K73789395 HT29 100 uM 6 h 0.0 0.0 0.0 0.27 0.95 0.32
11294 BRD-K73789395 MCF??7.00 100 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11565 BRD-K73789395 NCIH2073 100 uM 6 h 0.0 0.0 0.0 -0.3 -0.99 0.51
11829 BRD-K73789395 NCIH508 100 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12122 BRD-K73789395 NCIH596 100 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12374 BRD-K73789395 NOMO1 100 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12859 BRD-K73789395 SW480 100 uM 6 h -0.25 -1.03 0.2 0.0 0.0 0.0
13349 BRD-K73789395 U937 100 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13673 BRD-K73789395 VCAP 100 uM 6 h -0.2 -0.82 0.0 0.0 0.0 0.0
99450 BRD-K73789395 U2OS 12.5 uM 6 h 0.0 0.0 0.0 -0.22 -0.76 0.07
116972 BRD-K73789395 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).