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CMap Candidate Details

Structure:
CMap ID: C05936
Pert ID: BRD-K48300629
Compound Name: zonisamide
Targets: CA1|CA10|CA11|CA12|CA13|CA14|CA2|CA3|CA4|CA5A|CA5B|CA6|CA7|CA8|CA9|CACNA1G|CACNA1H|CACNA1I|MAOA|MAOB|SCN10A|SCN11A|SCN1A|SCN1B|SCN2A|SCN2B|SCN3A|SCN3B|SCN4A|SCN4B|SCN5A|SCN7A|SCN8A|SCN9A
MoA: sodium channel blocker; T-type calcium channel blocker
SMILES: NS(=O)(=O)Cc1noc2ccccc12
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
7163 BRD-K48300629 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
8687 BRD-K48300629 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
51730 BRD-K48300629 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
51948 BRD-K48300629 PC3 10 uM 6 h -0.22 -0.9 0.04 -0.28 -0.93 0.36
91163 BRD-K48300629 HUH7 15 uM 72 h 0.0 0.0 0.0 0.3 1.05 0.58
98391 BRD-K48300629 NEU 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
98698 BRD-K48300629 NPC 10 uM 6 h 0.0 0.0 0.0 -0.37 -1.25 1.35
99589 BRD-K48300629 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
125320 BRD-K48300629 HEK293 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125376 BRD-K48300629 HT29 1.11 uM 24 h 0.0 0.0 0.0 0.23 0.82 0.1
125402 BRD-K48300629 JURKAT 10 uM 24 h 0.0 0.0 0.0 -0.32 -1.07 0.75
133343 BRD-K48300629 A375 0.01 uM 24 h 0.0 0.0 0.0 -0.44 -1.48 15.35
133392 BRD-K48300629 HA1E 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133427 BRD-K48300629 HELA 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133522 BRD-K48300629 MCF10A 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133558 BRD-K48300629 MDAMB231 0.01 uM 24 h 0.0 0.0 0.0 -0.31 -1.03 0.64
133607 BRD-K48300629 THP1 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133636 BRD-K48300629 YAPC 0.03 uM 24 h -0.19 -0.78 0.0 -0.23 -0.77 0.08
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).