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CMap Candidate Details

Structure:
CMap ID: C05942
Pert ID: BRD-K63068307
Compound Name: ZSTK-474
Targets: PIK3CB|PIK3CD|PIK3CG
MoA: PI3K inhibitor
SMILES: FC(F)c1nc2ccccc2n1-c1nc(nc(n1)N1CCOCC1)N1CCOCC1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
30092 BRD-K63068307 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
30505 BRD-K63068307 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
31095 BRD-K63068307 HCC515 10 uM 6 h 0.0 0.0 0.0 0.18 0.65 0.01
31403 BRD-K63068307 HEPG2 10 uM 6 h -0.18 -0.74 0.0 -0.38 -1.28 1.45
31901 BRD-K63068307 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 -0.29 -0.97 0.45
32208 BRD-K63068307 NEU 10 uM 24 h 0.0 0.0 0.0 0.22 0.76 0.05
32484 BRD-K63068307 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
32807 BRD-K63068307 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
33087 BRD-K63068307 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
33328 BRD-K63068307 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
34394 BRD-K63068307 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
36302 BRD-K63068307 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
91548 BRD-K63068307 BT20 10 uM 6 h -0.23 -0.97 0.11 -0.35 -1.18 1.14
91581 BRD-K63068307 HS578T 10 uM 24 h 0.0 0.0 0.0 -0.32 -1.07 0.75
91711 BRD-K63068307 MDAMB231 10 uM 6 h 0.0 0.0 0.0 0.32 1.12 0.77
91745 BRD-K63068307 SKBR3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
92420 BRD-K63068307 A375 10 uM 24 h 0.0 0.0 0.0 -0.26 -0.89 0.26
92544 BRD-K63068307 HME1 10 uM 24 h 0.0 0.0 0.0 -0.42 -1.4 2.02
92639 BRD-K63068307 HT29 0.12 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
92700 BRD-K63068307 LNCAP 0.04 uM 3 h 0.27 1.13 0.3 -0.26 -0.88 0.25
92716 BRD-K63068307 MCF10A 0.12 uM 24 h 0.0 0.0 0.0 -0.32 -1.07 0.75
97264 BRD-K63068307 HAP1 0.66 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).