CMap Candidate Details
Structure:
| CMap ID: | C05946 |
| Pert ID: | BRD-K06817181 |
| Compound Name: | 1,2,3,4,5,6-hexabromocyclohexane |
| Targets: | JAK2 |
| MoA: | JAK inhibitor |
| SMILES: | BrC1C(Br)C(Br)C(Br)C(Br)C1Br |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 44290 | BRD-K06817181 | A375 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 44664 | BRD-K06817181 | A549 | 10 uM | 6 h | 0.29 | 1.23 | 0.49 | 0.0 | 0.0 | 0.0 |
| 44835 | BRD-K06817181 | ASC | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.24 | -0.81 | 0.13 |
| 45145 | BRD-K06817181 | HEPG2 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 45413 | BRD-K06817181 | HT29 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 45643 | BRD-K06817181 | MCF??7.00 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.28 | 1.0 | 0.42 |
| 45950 | BRD-K06817181 | NPC | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.25 | -0.84 | 0.18 |
| 46269 | BRD-K06817181 | PHH | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 46584 | BRD-K06817181 | SKB | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |