CMap Candidate Details
Structure:
| CMap ID: | C06004 |
| Pert ID: | BRD-A27924917 |
| Compound Name: | 2-hydroxysaclofen |
| Targets: | GABBR1|GABBR2 |
| MoA: | GABA receptor antagonist |
| SMILES: | NCC(O)(CS(O)(=O)=O)c1ccc(Cl)cc1 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 97146 | BRD-A27924917 | A375 | 3.33 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 97212 | BRD-A27924917 | PC3 | 1.11 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 98110 | BRD-A27924917 | NPC | 10 uM | 24 h | -0.23 | -0.94 | 0.08 | 0.0 | 0.0 | 0.0 |
| 98517 | BRD-A27924917 | NEU | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.36 | 1.27 | 1.34 |