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CMap Candidate Details

Structure:
CMap ID: C06041
Pert ID: BRD-A79431551
Compound Name: 3-deazaadenosine
Targets: AHCY
MoA: adenosylhomocysteinase inhibitor
SMILES: Nc1nccc2n(cnc12)[C@@H]1O[C@H](CO)C(O)C1O
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
127036 BRD-A79431551 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127056 BRD-A79431551 HA1E 10 uM 24 h 0.24 1.01 0.11 -0.3 -1.01 0.58
127156 BRD-A79431551 HT29 10 uM 24 h 0.0 0.0 0.0 0.34 1.21 1.13
127191 BRD-A79431551 MCF10A 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127258 BRD-A79431551 PC3 10 uM 24 h 0.0 0.0 0.0 -0.32 -1.09 0.84
127297 BRD-A79431551 THP1 0.04 uM 24 h 0.0 0.0 0.0 -0.31 -1.06 0.73
127330 BRD-A79431551 YAPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135064 BRD-A79431551 A549 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135120 BRD-A79431551 HEK293 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135134 BRD-A79431551 HELA 0.25 uM 24 h -0.22 -0.93 0.07 0.0 0.0 0.0
135190 BRD-A79431551 JURKAT 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135239 BRD-A79431551 MCF??7.00 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135290 BRD-A79431551 MDAMB231 2.22 uM 24 h 0.33 1.37 0.97 -0.23 -0.78 0.09
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).