CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C00610
Pert ID:	BRD-K79595931
Compound Name:	bavisant
Targets:	HRH3
MoA:	histamine receptor antagonist
SMILES:	O=C(N1CCN(CC1)C1CC1)c1ccc(CN2CCOCC2)cc1
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
127057	BRD-K79595931	HA1E	3.33 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
127122	BRD-K79595931	HELA	3.33 uM	24 h	0.2	0.85	0.01	-0.25	-0.86	0.2
127157	BRD-K79595931	HT29	3.33 uM	24 h	0.28	1.15	0.32	0.0	0.0	0.0
127192	BRD-K79595931	MCF10A	0.125 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
127222	BRD-K79595931	MCF??7.00	3.33 uM	24 h	0.0	0.0	0.0	-0.19	-0.65	0.01
127259	BRD-K79595931	PC3	0.37 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
127298	BRD-K79595931	THP1	0.04 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
127331	BRD-K79595931	YAPC	3.33 uM	24 h	0.0	0.0	0.0	0.27	0.96	0.34
135022	BRD-K79595931	A375	0.01 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
135065	BRD-K79595931	A549	0.03 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
135121	BRD-K79595931	HEK293	0.01 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
135191	BRD-K79595931	JURKAT	0.03 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
135291	BRD-K79595931	MDAMB231	0.03 uM	24 h	0.0	0.0	0.0	-0.25	-0.85	0.19

Summary