CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C00623
Pert ID:	BRD-K90195324
Compound Name:	bazedoxifene
Targets:	ESR1\|ESR2
MoA:	selective estrogen receptor modulator (SERM)
SMILES:	Cc1c(-c2ccc(O)cc2)n(Cc2ccc(OCCN3CCCCCC3)cc2)c2ccc(O)cc12
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
90603	BRD-K90195324	HCT116	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
90693	BRD-K90195324	MCF10A	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
96513	BRD-K90195324	PC3	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
127737	BRD-K90195324	A375	10 uM	24 h	0.2	0.81	0.0	0.0	0.0	0.0
127780	BRD-K90195324	A549	3.33 uM	24 h	-0.27	-1.12	0.39	0.0	0.0	0.0
127860	BRD-K90195324	HEK293	0.37 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
127934	BRD-K90195324	HUVEC	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
128026	BRD-K90195324	MCF??7.00	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
128074	BRD-K90195324	YAPC	10 uM	24 h	0.0	0.0	0.0	0.38	1.34	1.72
135524	BRD-K90195324	HA1E	2.22 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
135561	BRD-K90195324	HELA	0.25 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
135608	BRD-K90195324	HT29	0.01 uM	24 h	0.0	0.0	0.0	-0.36	-1.21	1.24
135652	BRD-K90195324	JURKAT	2.22 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0

Summary