CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C00645
Pert ID:	BRD-K49807096
Compound Name:	benazepril
Targets:	ACE
MoA:	angiotensin converting enzyme inhibitor
SMILES:	CCOC(=O)[C@H](CCc1ccccc1)N[C@H]1CCc2ccccc2N(CC(O)=O)C1=O
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
25382	BRD-K49807096	VCAP	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
95392	BRD-K49807096	U2OS	1.11 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
125245	BRD-K49807096	A375	0.04 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
125331	BRD-K49807096	HEK293	0.125 uM	24 h	0.0	0.0	0.0	-0.27	-0.92	0.34
125381	BRD-K49807096	HT29	3.33 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
125458	BRD-K49807096	MCF??7.00	0.37 uM	24 h	0.24	0.99	0.1	0.0	0.0	0.0
125501	BRD-K49807096	PC3	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
125529	BRD-K49807096	THP1	0.125 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
125554	BRD-K49807096	YAPC	0.04 uM	24 h	0.24	1.01	0.12	-0.4	-1.34	1.85
133370	BRD-K49807096	A549	2.22 uM	24 h	0.21	0.86	0.01	0.0	0.0	0.0
133399	BRD-K49807096	HA1E	0.01 uM	24 h	-0.19	-0.79	0.0	0.0	0.0	0.0
133433	BRD-K49807096	HELA	0.25 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
133490	BRD-K49807096	JURKAT	2.22 uM	24 h	0.27	1.11	0.26	0.0	0.0	0.0
133527	BRD-K49807096	MCF10A	0.08 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
133566	BRD-K49807096	MDAMB231	0.25 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0

Summary