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CMap Candidate Details

Structure:
CMap ID: C00689
Pert ID: BRD-A91008255
Compound Name: bepridil
Targets: ATP1A1|CACNA1A|CACNA1H|CACNA2D2|CALM1|KCNQ1|KCNQ4|PDE1A|PDE1B|TNNC1
MoA: calcium channel blocker
SMILES: CC(C)COCC(CN(Cc1ccccc1)c1ccccc1)N1CCCC1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5170 BRD-A91008255 A375 10 uM 6 h 0.22 0.91 0.03 0.0 0.0 0.0
5418 BRD-A91008255 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
5742 BRD-A91008255 HCC515 10 uM 6 h 0.0 0.0 0.0 -0.21 -0.69 0.03
6080 BRD-A91008255 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
6154 BRD-A91008255 PC3 10 uM 24 h 0.0 0.0 0.0 -0.22 -0.72 0.04
6498 BRD-A91008255 VCAP 10 uM 6 h 0.0 0.0 0.0 -0.26 -0.87 0.22
39417 BRD-A91008255 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39928 BRD-A91008255 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40213 BRD-A91008255 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40732 BRD-A91008255 NEU 10 uM 24 h -0.21 -0.86 0.02 -0.39 -1.31 1.7
41034 BRD-A91008255 NPC 10 uM 24 h -0.26 -1.08 0.3 0.0 0.0 0.0
41357 BRD-A91008255 SKB 10 uM 24 h 0.0 0.0 0.0 0.29 1.03 0.51
100390 BRD-A91008255 U2OS 12.5 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).