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CMap Candidate Details

Structure:
CMap ID: C00712
Pert ID: BRD-A02759312
Compound Name: betaxolol
Targets: ADRB1|ADRB2
MoA: adrenergic receptor antagonist
SMILES: CC(C)NCC(O)COc1ccc(CCOCC2CC2)cc1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4269 BRD-A02759312 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
4604 BRD-A02759312 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
24710 BRD-A02759312 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
25061 BRD-A02759312 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
25276 BRD-A02759312 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
37036 BRD-A02759312 A375 10 uM 6 h -0.27 -1.13 0.4 0.0 0.0 0.0
37210 BRD-A02759312 A549 10 uM 24 h -0.22 -0.9 0.04 0.2 0.71 0.02
37429 BRD-A02759312 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
37973 BRD-A02759312 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
38283 BRD-A02759312 NPC 10 uM 24 h 0.0 0.0 0.0 -0.24 -0.81 0.13
38593 BRD-A02759312 PHH 10 uM 24 h 0.0 0.0 0.0 0.22 0.77 0.05
38810 BRD-A02759312 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
91049 BRD-A02759312 HUH7 10 uM 72 h -0.24 -0.99 0.13 -0.35 -1.17 1.11
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).