CMap Candidate Details
Structure:
| CMap ID: | C00719 |
| Pert ID: | BRD-K16898998 |
| Compound Name: | bevirimat-dimeglumine |
| Targets: | |
| MoA: | HIV capsid assembly inhibitor |
| SMILES: | CC(=C)[C@@H]1CC[C@@]2(CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC[C@H](OC(=O)CC(C)(C)C(O)=O)C(C)(C)[C@@H]5CC[C@@]34C)[C@@H]12)C(O)=O |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 120241 | BRD-K16898998 | A375 | 10 uM | 24 h | 0.25 | 1.04 | 0.15 | -0.2 | -0.69 | 0.02 |
| 120278 | BRD-K16898998 | A549 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.31 | -1.04 | 0.66 |
| 120316 | BRD-K16898998 | HA1E | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 120341 | BRD-K16898998 | HELA | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.34 | -1.14 | 1.01 |
| 120377 | BRD-K16898998 | HT29 | 0.37 uM | 24 h | 0.18 | 0.77 | 0.0 | 0.38 | 1.33 | 1.72 |
| 120405 | BRD-K16898998 | MCF??7.00 | 1.11 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 120436 | BRD-K16898998 | PC3 | 10 uM | 24 h | 0.19 | 0.8 | 0.0 | 0.31 | 1.08 | 0.66 |
| 120474 | BRD-K16898998 | YAPC | 0.125 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.33 | 1.16 | 0.9 |