CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C00725
Pert ID:	BRD-A81370665
Compound Name:	BI-D1870
Targets:	RPS6KA1\|RPS6KA2\|RPS6KA3\|RPS6KA6
MoA:	ribosomal protein inhibitor
SMILES:	CC(C)CCN1C(C)C(=O)N(C)c2cnc(Nc3cc(F)c(O)c(F)c3)nc12
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
44	BRD-A81370665	BJAB	2.5 uM	4 h	0.0	0.0	0.0	-0.29	-0.98	0.47
109	BRD-A81370665	HBL1	10 uM	4 h	0.0	0.0	0.0	-0.41	-1.37	2.02
145	BRD-A81370665	K562	10 uM	4 h	0.0	0.0	0.0	0.0	0.0	0.0
166	BRD-A81370665	KMS34	10 uM	24 h	0.0	0.0	0.0	0.3	1.07	0.63
208	BRD-A81370665	NALM6	10 uM	24 h	0.27	1.11	0.25	-0.25	-0.83	0.15
247	BRD-A81370665	OCILY10	10 uM	24 h	0.22	0.93	0.05	-0.38	-1.28	1.45
306	BRD-A81370665	OCILY19	10 uM	4 h	0.0	0.0	0.0	0.0	0.0	0.0
324	BRD-A81370665	OCILY3	10 uM	24 h	0.0	0.0	0.0	-0.31	-1.03	0.63
364	BRD-A81370665	SKMEL5	10 uM	24 h	0.0	0.0	0.0	0.27	0.94	0.29
417	BRD-A81370665	THP1	10 uM	4 h	0.0	0.0	0.0	0.0	0.0	0.0
436	BRD-A81370665	TMD8	2.5 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0

Summary