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CMap Candidate Details

Structure:
CMap ID: C00728
Pert ID: BRD-K73982490
Compound Name: BI-78D3
Targets: MAPK8
MoA: JNK inhibitor
SMILES: Oc1nnc(Sc2ncc(s2)[N+]([O-])=O)n1-c1ccc2OCCOc2c1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
33693 BRD-K73982490 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
33924 BRD-K73982490 A549 10 uM 6 h 0.0 0.0 0.0 -0.27 -0.91 0.31
34168 BRD-K73982490 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
34412 BRD-K73982490 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
34674 BRD-K73982490 HCC515 10 uM 6 h 0.0 0.0 0.0 -0.24 -0.82 0.14
34948 BRD-K73982490 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
35192 BRD-K73982490 HT29 10 uM 6 h 0.0 0.0 0.0 0.3 1.08 0.65
35465 BRD-K73982490 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
35832 BRD-K73982490 NPC 10 uM 24 h 0.23 0.96 0.07 0.0 0.0 0.0
36099 BRD-K73982490 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
36339 BRD-K73982490 PHH 10 uM 24 h -0.22 -0.91 0.05 0.0 0.0 0.0
36635 BRD-K73982490 SKB 10 uM 24 h 0.24 1.02 0.12 0.0 0.0 0.0
36999 BRD-K73982490 VCAP 10 uM 6 h 0.0 0.0 0.0 -0.38 -1.27 1.43
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).