CMap Candidate Details
Structure:
| CMap ID: | C00749 |
| Pert ID: | BRD-K36467523 |
| Compound Name: | bindarit |
| Targets: | CCL2|CCL7|CCL8 |
| MoA: | NFkB pathway inhibitor |
| SMILES: | CC(C)(OCc1nn(Cc2ccccc2)c2ccccc12)C(O)=O |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 120579 | BRD-K36467523 | A549 | 0.04 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 120684 | BRD-K36467523 | HT29 | 3.33 uM | 24 h | 0.21 | 0.86 | 0.01 | -0.38 | -1.29 | 1.52 |
| 120738 | BRD-K36467523 | JURKAT | 1.11 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 120846 | BRD-K36467523 | YAPC | 0.04 uM | 24 h | 0.21 | 0.89 | 0.02 | 0.0 | 0.0 | 0.0 |
| 128997 | BRD-K36467523 | A375 | 0.08 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 129015 | BRD-K36467523 | HA1E | 0.08 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 129025 | BRD-K36467523 | HELA | 0.08 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.38 | -1.28 | 1.45 |
| 129071 | BRD-K36467523 | MCF??7.00 | 0.25 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 129088 | BRD-K36467523 | PC3 | 0.08 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |