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CMap Candidate Details

Structure:
CMap ID: C00752
Pert ID: BRD-K89210380
Compound Name: biotin
Targets: ACACA|ACACB|HLCS|MCCC1|MCCC2|PC|PCCA|PCCB|SLC5A6
MoA: vitamin B
SMILES: OC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1654 BRD-K89210380 HA1E 10 uM 24 h 0.25 1.03 0.14 0.28 0.98 0.37
2003 BRD-K89210380 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
2442 BRD-K89210380 PC3 10 uM 6 h 0.0 0.0 0.0 -0.22 -0.76 0.07
2466 BRD-K89210380 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41854 BRD-K89210380 A375 10 uM 6 h -0.15 -0.64 0.0 -0.23 -0.77 0.08
42154 BRD-K89210380 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42491 BRD-K89210380 ASC 10 uM 24 h 0.0 0.0 0.0 0.41 1.45 2.22
42802 BRD-K89210380 HEPG2 10 uM 6 h -0.33 -1.39 1.13 0.0 0.0 0.0
43092 BRD-K89210380 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43244 BRD-K89210380 MCF??7.00 10 uM 24 h 0.2 0.84 0.0 -0.32 -1.07 0.75
43667 BRD-K89210380 NPC 10 uM 24 h -0.22 -0.9 0.04 0.0 0.0 0.0
43967 BRD-K89210380 PHH 10 uM 24 h 0.0 0.0 0.0 0.27 0.96 0.33
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).