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CMap Candidate Details

Structure:
CMap ID: C00758
Pert ID: BRD-K39987650
Compound Name: bisacodyl
Targets:
MoA: laxative
SMILES: CC(=O)Oc1ccc(cc1)C(c1ccc(OC(C)=O)cc1)c1ccccn1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5327 BRD-K39987650 HA1E 10 uM 24 h -0.23 -0.94 0.08 0.0 0.0 0.0
5625 BRD-K39987650 HCC515 10 uM 24 h 0.25 1.06 0.18 0.0 0.0 0.0
5912 BRD-K39987650 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
6024 BRD-K39987650 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
6095 BRD-K39987650 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 -0.37 -1.26 1.36
6341 BRD-K39987650 VCAP 10 uM 24 h 0.0 0.0 0.0 -0.32 -1.06 0.74
37153 BRD-K39987650 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
37652 BRD-K39987650 ASC 10 uM 24 h 0.24 1.01 0.12 -0.3 -1.02 0.61
38477 BRD-K39987650 NPC 10 uM 24 h 0.0 0.0 0.0 -0.28 -0.95 0.41
38951 BRD-K39987650 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
51823 BRD-K39987650 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
91398 BRD-K39987650 HUH7 10 uM 72 h 0.0 0.0 0.0 0.0 0.0 0.0
96191 BRD-K39987650 A549 10 uM 24 h 0.0 0.0 0.0 -0.31 -1.05 0.69
96258 BRD-K39987650 U2OS 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).