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CMap Candidate Details

Structure:
CMap ID: C00782
Pert ID: BRD-K94379058
Compound Name: BML-190
Targets: CNR2
MoA: cannabinoid receptor inverse agonist
SMILES: COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(=O)N3CCOCC3)c2c1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1666 BRD-K94379058 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
2013 BRD-K94379058 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
2449 BRD-K94379058 PC3 10 uM 6 h 0.2 0.85 0.01 0.0 0.0 0.0
2475 BRD-K94379058 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39237 BRD-K94379058 A375 10 uM 6 h 0.0 0.0 0.0 -0.25 -0.84 0.18
39529 BRD-K94379058 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39843 BRD-K94379058 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
40133 BRD-K94379058 HEPG2 10 uM 6 h 0.23 0.97 0.08 -0.23 -0.78 0.09
40391 BRD-K94379058 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40666 BRD-K94379058 MCF??7.00 10 uM 6 h 0.29 1.2 0.43 -0.29 -0.97 0.45
40939 BRD-K94379058 NEU 10 uM 24 h -0.22 -0.92 0.06 0.0 0.0 0.0
41264 BRD-K94379058 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41605 BRD-K94379058 SKB 10 uM 24 h 0.0 0.0 0.0 -0.27 -0.92 0.33
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).