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CMap Candidate Details

Structure:
CMap ID: C00789
Pert ID: BRD-K02950022
Compound Name: BMS-299897
Targets:
MoA: gamma secretase inhibitor
SMILES: C[C@@H](N(c1cc(F)ccc1F)S(=O)(=O)c1ccc(Cl)cc1)c1ccc(F)cc1CCCC(O)=O
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
9337 BRD-K02950022 AGS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
9643 BRD-K02950022 H1299 10 uM 6 h 0.0 0.0 0.0 -0.28 -0.93 0.35
10154 BRD-K02950022 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
10441 BRD-K02950022 HCT116 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10712 BRD-K02950022 HEPG2 10 uM 6 h 0.27 1.12 0.27 0.0 0.0 0.0
11393 BRD-K02950022 NCIH2073 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11965 BRD-K02950022 NCIH596 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12248 BRD-K02950022 NOMO1 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12709 BRD-K02950022 SW480 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13190 BRD-K02950022 U937 10 uM 6 h -0.25 -1.05 0.24 0.0 0.0 0.0
13567 BRD-K02950022 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
90866 BRD-K02950022 MCF10A 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122840 BRD-K02950022 A375 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122867 BRD-K02950022 HA1E 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122914 BRD-K02950022 HEK293 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122950 BRD-K02950022 HELA 3.33 uM 24 h 0.25 1.03 0.13 0.0 0.0 0.0
122988 BRD-K02950022 HT29 3.33 uM 24 h 0.22 0.91 0.04 0.0 0.0 0.0
123039 BRD-K02950022 JURKAT 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123081 BRD-K02950022 MCF??7.00 3.33 uM 24 h 0.0 0.0 0.0 -0.4 -1.35 2.02
123129 BRD-K02950022 MDAMB231 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123155 BRD-K02950022 PC3 3.33 uM 24 h 0.19 0.8 0.0 0.0 0.0 0.0
123201 BRD-K02950022 THP1 10 uM 24 h 0.0 0.0 0.0 -0.31 -1.03 0.64
123222 BRD-K02950022 YAPC 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131257 BRD-K02950022 A549 0.03 uM 24 h -0.35 -1.47 1.43 0.0 0.0 0.0
131376 BRD-K02950022 HUVEC 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).