CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C00802
Pert ID:	BRD-K49555808
Compound Name:	BMS-707035
Targets:
MoA:	HIV integrase inhibitor
SMILES:	Cn1c(nc(C(=O)NCc2ccc(F)cc2)c(O)c1=O)N1CCCCS1(=O)=O
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
125598	BRD-K49555808	A375	0.125 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
125684	BRD-K49555808	HELA	0.37 uM	24 h	0.0	0.0	0.0	-0.36	-1.22	1.24
125755	BRD-K49555808	HUVEC	3.33 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
125789	BRD-K49555808	JURKAT	0.125 uM	24 h	0.27	1.15	0.32	0.0	0.0	0.0
125810	BRD-K49555808	MCF10A	0.04 uM	24 h	0.26	1.07	0.2	0.22	0.77	0.06
125835	BRD-K49555808	MCF??7.00	0.125 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
125902	BRD-K49555808	THP1	0.37 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
125953	BRD-K49555808	YAPC	0.125 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
133676	BRD-K49555808	A549	0.01 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
133714	BRD-K49555808	HA1E	0.01 uM	24 h	0.0	0.0	0.0	-0.28	-0.94	0.37
133744	BRD-K49555808	HEK293	0.74 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
133809	BRD-K49555808	HT29	0.01 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
133927	BRD-K49555808	MDAMB231	0.25 uM	24 h	0.21	0.89	0.02	0.34	1.22	1.15
133957	BRD-K49555808	PC3	0.03 uM	24 h	0.2	0.85	0.01	0.28	0.98	0.39

Summary