Logo 1 Logo 2

CMap Candidate Details

Structure:
CMap ID: C00803
Pert ID: BRD-K13049116
Compound Name: BMS-754807
Targets: AKT1|IGF1R
MoA: IGF-1 inhibitor
SMILES: C[C@]1(CCCN1c1nc(Nc2cc(n[nH]2)C2CC2)c2cccn2n1)C(=O)Nc1ccc(F)nc1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
9368 BRD-K13049116 AGS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
9674 BRD-K13049116 H1299 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
9980 BRD-K13049116 HA1E 10 uM 24 h -0.19 -0.79 0.0 0.0 0.0 0.0
10347 BRD-K13049116 HCC515 10 uM 6 h -0.17 -0.73 0.0 -0.25 -0.85 0.2
10466 BRD-K13049116 HCT116 10 uM 6 h -0.28 -1.15 0.44 0.3 1.07 0.63
11427 BRD-K13049116 NCIH2073 10 uM 6 h 0.0 0.0 0.0 0.24 0.85 0.15
11718 BRD-K13049116 NCIH508 10 uM 6 h 0.0 0.0 0.0 0.27 0.97 0.34
11994 BRD-K13049116 NCIH596 10 uM 6 h 0.21 0.86 0.01 0.0 0.0 0.0
12272 BRD-K13049116 NOMO1 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13087 BRD-K13049116 THP1 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13218 BRD-K13049116 U937 10 uM 6 h -0.23 -0.97 0.11 0.0 0.0 0.0
13450 BRD-K13049116 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
96821 BRD-K13049116 A375 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
118423 BRD-K13049116 A549 3.33 uM 24 h -0.18 -0.77 0.0 -0.28 -0.95 0.4
118542 BRD-K13049116 HEPG2 3.33 uM 24 h 0.22 0.92 0.04 -0.33 -1.1 0.88
118583 BRD-K13049116 HT29 10 uM 24 h 0.0 0.0 0.0 -0.26 -0.88 0.26
118620 BRD-K13049116 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
118649 BRD-K13049116 PC3 10 uM 24 h 0.0 0.0 0.0 -0.35 -1.18 1.15
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).