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CMap Candidate Details

Structure:
CMap ID: C00809
Pert ID: BRD-K55781385
Compound Name: BMS-927711
Targets: CALCA
MoA: calcitonin antagonist
SMILES: N[C@H]1[C@@H](CC[C@@H](OC(=O)N2CCC(CC2)n2c3cccnc3[nH]c2=O)c2ncccc12)c1cccc(F)c1F
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
123783 BRD-K55781385 A375 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123824 BRD-K55781385 A549 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123881 BRD-K55781385 HEK293 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123934 BRD-K55781385 HELA 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123980 BRD-K55781385 JURKAT 3.33 uM 24 h 0.0 0.0 0.0 -0.19 -0.66 0.01
124036 BRD-K55781385 MCF10A 10 uM 24 h 0.0 0.0 0.0 -0.22 -0.75 0.07
124086 BRD-K55781385 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.28 0.98 0.38
124163 BRD-K55781385 THP1 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124216 BRD-K55781385 YAPC 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132157 BRD-K55781385 HA1E 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132216 BRD-K55781385 HT29 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132268 BRD-K55781385 MDAMB231 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132284 BRD-K55781385 PC3 0.01 uM 24 h 0.24 1.0 0.11 -0.31 -1.03 0.64
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).