CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C00826
Pert ID:	BRD-K17378184
Compound Name:	BP-897
Targets:	ADRA1A\|ADRA1D\|ADRA2A\|DRD1\|DRD2\|DRD3\|DRD4\|HTR1A\|HTR2B
MoA:	dopamine receptor agonist
SMILES:	COc1ccccc1N1CCN(CCCCNC(=O)c2ccc3ccccc3c2)CC1
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
4072	BRD-K17378184	HA1E	10 uM	24 h	-0.21	-0.86	0.02	0.0	0.0	0.0
4552	BRD-K17378184	HCC515	10 uM	6 h	0.0	0.0	0.0	-0.25	-0.84	0.18
5046	BRD-K17378184	VCAP	10 uM	6 h	0.0	0.0	0.0	-0.25	-0.84	0.17
44322	BRD-K17378184	A375	10 uM	6 h	0.22	0.92	0.04	0.0	0.0	0.0
44679	BRD-K17378184	A549	10 uM	6 h	0.0	0.0	0.0	0.25	0.87	0.17
44879	BRD-K17378184	ASC	10 uM	24 h	0.0	0.0	0.0	-0.28	-0.95	0.4
45181	BRD-K17378184	HEPG2	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
45449	BRD-K17378184	HT29	10 uM	6 h	0.0	0.0	0.0	0.36	1.28	1.42
45996	BRD-K17378184	NPC	10 uM	24 h	-0.31	-1.29	0.77	0.0	0.0	0.0
46314	BRD-K17378184	PHH	10 uM	24 h	0.0	0.0	0.0	-0.28	-0.93	0.35
46629	BRD-K17378184	SKB	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
51596	BRD-K17378184	MCF??7.00	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
51808	BRD-K17378184	PC3	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
100158	BRD-K17378184	U2OS	4 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0

Summary