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CMap Candidate Details

Structure:
CMap ID: C00831
Pert ID: BRD-K89329876
Compound Name: BRD-9876
Targets: KIF11
MoA: kinesin inhibitor
SMILES: CC(C)(C)c1ccc2cc(C#N)c(cc2c1)C#N
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
9003 BRD-K89329876 A375 40 uM 24 h 0.0 0.0 0.0 -0.31 -1.04 0.66
9122 BRD-K89329876 A549 40 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
9536 BRD-K89329876 AGS 40 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
9842 BRD-K89329876 H1299 40 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
9992 BRD-K89329876 HA1E 40 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
10363 BRD-K89329876 HCC515 40 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10619 BRD-K89329876 HCT116 40 uM 6 h 0.0 0.0 0.0 0.34 1.19 1.02
10869 BRD-K89329876 HEPG2 40 uM 6 h 0.0 0.0 0.0 -0.3 -1.02 0.62
11032 BRD-K89329876 HT29 40 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
11240 BRD-K89329876 MCF??7.00 40 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
11603 BRD-K89329876 NCIH2073 40 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11862 BRD-K89329876 NCIH508 40 uM 6 h 0.0 0.0 0.0 -0.31 -1.06 0.72
12160 BRD-K89329876 NCIH596 40 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12566 BRD-K89329876 PC3 40 uM 24 h 0.0 0.0 0.0 -0.23 -0.79 0.1
13385 BRD-K89329876 U937 40 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13699 BRD-K89329876 VCAP 40 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).