CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C00838
Pert ID:	BRD-K00911143
Compound Name:	brexpiprazole
Targets:	DRD2
MoA:	dopamine receptor partial agonist
SMILES:	O=c1ccc2ccc(OCCCCN3CCN(CC3)c3cccc4sccc34)cc2[nH]1
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
122857	BRD-K00911143	HA1E	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
122888	BRD-K00911143	HEK293	1.11 uM	24 h	-0.23	-0.97	0.11	-0.38	-1.27	1.43
122936	BRD-K00911143	HELA	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
122968	BRD-K00911143	HT29	1.11 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
123013	BRD-K00911143	JURKAT	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
123059	BRD-K00911143	MCF10A	10 uM	24 h	0.0	0.0	0.0	-0.33	-1.11	0.9
123073	BRD-K00911143	MCF??7.00	10 uM	24 h	0.0	0.0	0.0	-0.29	-0.98	0.48
123102	BRD-K00911143	MDAMB231	0.04 uM	24 h	0.0	0.0	0.0	0.31	1.1	0.7
123144	BRD-K00911143	PC3	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
123174	BRD-K00911143	THP1	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
123215	BRD-K00911143	YAPC	10 uM	24 h	0.2	0.83	0.0	0.28	0.99	0.39
131206	BRD-K00911143	A375	0.01 uM	24 h	-0.28	-1.18	0.51	0.0	0.0	0.0
131239	BRD-K00911143	A549	0.74 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
131350	BRD-K00911143	HUVEC	2.22 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0

Summary