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CMap Candidate Details

Structure:
CMap ID: C00847
Pert ID: BRD-A63675168
Compound Name: brivudine
Targets:
MoA: DNA directed DNA polymerase inhibitor
SMILES: OC[C@H]1O[C@H](CC1O)n1cc(\C=C\Br)c(=O)[nH]c1=O
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
124596 BRD-A63675168 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124796 BRD-A63675168 MDAMB231 0.37 uM 24 h 0.0 0.0 0.0 -0.24 -0.81 0.14
124837 BRD-A63675168 PC3 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124879 BRD-A63675168 THP1 3.33 uM 24 h -0.23 -0.96 0.1 0.0 0.0 0.0
132661 BRD-A63675168 A375 0.08 uM 24 h 0.0 0.0 0.0 -0.3 -1.02 0.6
132720 BRD-A63675168 HA1E 0.03 uM 24 h 0.0 0.0 0.0 -0.32 -1.09 0.81
132752 BRD-A63675168 HEK293 0.08 uM 24 h -0.21 -0.86 0.02 -0.29 -0.97 0.45
132788 BRD-A63675168 HELA 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132809 BRD-A63675168 HT29 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132833 BRD-A63675168 JURKAT 0.01 uM 24 h 0.0 0.0 0.0 -0.32 -1.07 0.78
132868 BRD-A63675168 MCF10A 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132898 BRD-A63675168 MCF??7.00 0.03 uM 24 h 0.0 0.0 0.0 -0.32 -1.09 0.84
132951 BRD-A63675168 YAPC 0.01 uM 24 h 0.21 0.88 0.02 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).