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CMap Candidate Details

Structure:
CMap ID: C00854
Pert ID: BRD-K17868609
Compound Name: BRL-54443
Targets: HTR1E|HTR1F
MoA: serotonin receptor agonist
SMILES: CN1CCC(CC1)c1c[nH]c2ccc(O)cc12
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
2989 BRD-K17868609 HA1E 10 uM 6 h 0.0 0.0 0.0 0.32 1.14 0.86
3338 BRD-K17868609 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
3600 BRD-K17868609 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
3945 BRD-K17868609 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39096 BRD-K17868609 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39430 BRD-K17868609 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39638 BRD-K17868609 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39953 BRD-K17868609 HEPG2 10 uM 6 h 0.21 0.89 0.02 -0.21 -0.71 0.03
40234 BRD-K17868609 HT29 10 uM 6 h 0.0 0.0 0.0 0.27 0.95 0.32
40594 BRD-K17868609 MCF??7.00 10 uM 6 h 0.25 1.05 0.17 0.0 0.0 0.0
40761 BRD-K17868609 NEU 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41062 BRD-K17868609 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41391 BRD-K17868609 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).