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CMap Candidate Details

Structure:
CMap ID: C00859
Pert ID: BRD-K47631482
Compound Name: bromhexine
Targets:
MoA: mucolytic agent
SMILES: CN(Cc1cc(Br)cc(Br)c1N)C1CCCCC1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5336 BRD-K47631482 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
5640 BRD-K47631482 HCC515 10 uM 24 h -0.22 -0.93 0.07 0.0 0.0 0.0
5923 BRD-K47631482 HEPG2 10 uM 6 h 0.23 0.94 0.06 -0.36 -1.22 1.25
6028 BRD-K47631482 HT29 10 uM 6 h 0.26 1.1 0.24 0.0 0.0 0.0
6100 BRD-K47631482 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.33 1.15 0.9
6194 BRD-K47631482 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
6558 BRD-K47631482 VCAP 10 uM 6 h -0.15 -0.64 0.0 0.0 0.0 0.0
39142 BRD-K47631482 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39456 BRD-K47631482 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39707 BRD-K47631482 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
40823 BRD-K47631482 NEU 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41128 BRD-K47631482 NPC 10 uM 24 h 0.24 0.98 0.09 0.0 0.0 0.0
41463 BRD-K47631482 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
91400 BRD-K47631482 HUH7 8 uM 72 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).