CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C00879
Pert ID:	BRD-A68304895
Compound Name:	BTS-54505
Targets:	SLC6A2\|SLC6A3\|SLC6A4
MoA:	dopamine reuptake inhibitor
SMILES:	CC(C)CC(N)C1(CCC1)c1ccc(Cl)cc1
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
126734	BRD-A68304895	HT29	10 uM	24 h	0.0	0.0	0.0	0.32	1.15	0.88
126827	BRD-A68304895	MCF??7.00	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
126869	BRD-A68304895	MDAMB231	10 uM	24 h	0.24	1.01	0.12	0.27	0.96	0.33
126930	BRD-A68304895	THP1	0.37 uM	24 h	0.0	0.0	0.0	0.32	1.12	0.77
134669	BRD-A68304895	A375	2.22 uM	24 h	0.0	0.0	0.0	0.31	1.1	0.71
134692	BRD-A68304895	A549	0.08 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
134718	BRD-A68304895	HA1E	0.01 uM	24 h	0.0	0.0	0.0	-0.25	-0.85	0.19
134752	BRD-A68304895	HEK293	0.01 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
134787	BRD-A68304895	HELA	0.25 uM	24 h	0.0	0.0	0.0	0.29	1.03	0.5
134845	BRD-A68304895	HUVEC	0.01 uM	24 h	0.22	0.92	0.04	0.0	0.0	0.0
134896	BRD-A68304895	JURKAT	0.03 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
134917	BRD-A68304895	MCF10A	0.25 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
134954	BRD-A68304895	PC3	0.08 uM	24 h	0.24	0.99	0.1	0.28	0.98	0.39
134984	BRD-A68304895	YAPC	0.03 uM	24 h	0.0	0.0	0.0	-0.34	-1.13	0.98

Summary