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CMap Candidate Details

Structure:
CMap ID: C00883
Pert ID: BRD-K55344148
Compound Name: BU-224
Targets: MAOA|MAOB
MoA: imidazoline receptor ligand
SMILES: C1CN=C(N1)c1ccc2ccccc2n1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
6782 BRD-K55344148 A375 10 uM 24 h -0.19 -0.79 0.0 0.0 0.0 0.0
7013 BRD-K55344148 A549 10 uM 24 h -0.24 -0.99 0.13 -0.19 -0.62 0.0
8015 BRD-K55344148 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
8521 BRD-K55344148 PC3 10 uM 6 h 0.19 0.79 0.0 0.21 0.75 0.04
8832 BRD-K55344148 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
90598 BRD-K55344148 HCT116 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
90671 BRD-K55344148 MCF10A 10 uM 24 h 0.21 0.86 0.01 0.33 1.17 0.92
97992 BRD-K55344148 HA1E 0.125 uM 24 h -0.23 -0.94 0.08 0.0 0.0 0.0
98023 BRD-K55344148 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
98071 BRD-K55344148 P1A82 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
99668 BRD-K55344148 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).