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CMap Candidate Details

Structure:
CMap ID: C00884
Pert ID: BRD-K11696279
Compound Name: BU-239
Targets:
MoA: imidazoline receptor ligand; imidazoline receptor agonist
SMILES: C1CN=C(N1)c1cnc2ccccc2n1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1546 BRD-K11696279 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
1887 BRD-K11696279 HCC515 10 uM 24 h 0.0 0.0 0.0 -0.38 -1.27 1.39
2222 BRD-K11696279 PC3 10 uM 24 h 0.0 0.0 0.0 -0.35 -1.19 1.16
2712 BRD-K11696279 VCAP 10 uM 6 h 0.0 0.0 0.0 0.33 1.16 0.9
41724 BRD-K11696279 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
41911 BRD-K11696279 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42296 BRD-K11696279 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42629 BRD-K11696279 HEPG2 10 uM 6 h -0.34 -1.41 1.42 -0.34 -1.13 1.0
42932 BRD-K11696279 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43489 BRD-K11696279 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
43793 BRD-K11696279 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
90604 BRD-K11696279 HCT116 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
90697 BRD-K11696279 MCF10A 1.11 uM 24 h 0.0 0.0 0.0 0.2 0.7 0.02
98038 BRD-K11696279 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
98089 BRD-K11696279 P1A82 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).