CMap Candidate Details
Structure:
| CMap ID: | C00892 |
| Pert ID: | BRD-K19462402 |
| Compound Name: | buflomedil |
| Targets: | ADRA1A |
| MoA: | adrenergic receptor antagonist; calcium channel blocker |
| SMILES: | COc1cc(OC)c(C(=O)CCCN2CCCC2)c(OC)c1 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 24655 | BRD-K19462402 | A549 | 10 uM | 6 h | -0.23 | -0.97 | 0.11 | 0.0 | 0.0 | 0.0 |
| 25339 | BRD-K19462402 | VCAP | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.38 | 1.34 | 1.72 |
| 121475 | BRD-K19462402 | PC3 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 121500 | BRD-K19462402 | YAPC | 0.37 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.38 | -1.27 | 1.44 |
| 129397 | BRD-K19462402 | A375 | 0.25 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 129428 | BRD-K19462402 | HA1E | 0.74 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.33 | -1.12 | 0.93 |
| 129462 | BRD-K19462402 | HELA | 0.01 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.32 | -1.07 | 0.76 |
| 129483 | BRD-K19462402 | HT29 | 0.03 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 129513 | BRD-K19462402 | MCF??7.00 | 0.08 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |