CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C00910
Pert ID:	BRD-K17497770
Compound Name:	butein
Targets:	ACE
MoA:	EGFR inhibitor; src inhibitor
SMILES:	Oc1ccc(C(=O)\C=C\c2ccc(O)c(O)c2)c(O)c1
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
4074	BRD-K17497770	HA1E	10 uM	24 h	0.25	1.03	0.13	0.0	0.0	0.0
4381	BRD-K17497770	HCC515	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
4656	BRD-K17497770	PC3	10 uM	24 h	-0.18	-0.76	0.0	0.0	0.0	0.0
4904	BRD-K17497770	VCAP	10 uM	24 h	0.0	0.0	0.0	-0.36	-1.22	1.24
44324	BRD-K17497770	A375	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
44535	BRD-K17497770	A549	10 uM	24 h	0.0	0.0	0.0	0.29	1.04	0.55
44881	BRD-K17497770	ASC	10 uM	24 h	0.0	0.0	0.0	-0.35	-1.19	1.15
45183	BRD-K17497770	HEPG2	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
45451	BRD-K17497770	HT29	10 uM	6 h	0.0	0.0	0.0	-0.31	-1.06	0.72
45661	BRD-K17497770	MCF??7.00	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
45998	BRD-K17497770	NPC	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
46316	BRD-K17497770	PHH	10 uM	24 h	0.22	0.91	0.03	-0.25	-0.83	0.16
46631	BRD-K17497770	SKB	10 uM	24 h	0.0	0.0	0.0	0.24	0.85	0.14
100160	BRD-K17497770	U2OS	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0

Summary